Liposomes in Polymersomes: Multicompartment System with Temperature-Triggered Release
نویسندگان
چکیده
منابع مشابه
Photo- and thermoresponsive polymersomes for triggered release.
Microfluidics: Thermo- and photoresponsive polymersomes are assembled using capillary microfluidic devices. Encapsulants can be selectively released from the thermoresponsive polymersomes if they are incubated at and above temperatures of 40 °C, whereas the photoresponsive polymersomes selectively release encapsulants if illuminated with laser light (see picture; NP = nanoparticle).
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Polymersomes are vesicles which consist of compartments surrounded by membrane walls that are composed of lamellae of block copolymers. They are important for numerous applications in encapsulation and delivery of active ingredients such as food additives, drugs, fragrances, and enzymes. Polymersomes are typically prepared by precipitating block copolymers from their solvents through addition o...
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Magnetic polymersomes were prepared by self-assembly of the amphiphilic block copolymer poly(isoprene-b-N-isopropylacrylamide) with monodisperse hydrophobic superparamagnetic iron oxide nanoparticles (SPION). The specifically designed thermoresponsive block copolymer allowed for efficient incorporation of the hydrophobic nanoparticles in the membrane core and encapsulation of the water soluble ...
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Lysolipid temperature-sensitive liposomes (LTSLs) demonstrate enhanced release of encapsulated drug contents via grain boundary permeabilization when heated to their phase transition temperature, resulting in dramatic in vivo tumor toxicity. Dithionite ion permeability and doxorubicin release were measured for lysolipid and nonlysolipid containing membranes to characterize and attempt to determ...
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A zinc(II)-dipicolylamine coordination complex selectively associates with anionic liposomes, including sterically protected PEGylated liposomes, and causes rapid leakage of encapsulated contents.
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ژورنال
عنوان ژورنال: Langmuir
سال: 2017
ISSN: 0743-7463,1520-5827
DOI: 10.1021/acs.langmuir.7b00655